Study results indicate that mutation strength may shape both tumor–immune system interactions and immunotherapy response.

Scientists have created a complete map showing how hundreds of possible mutations in a key cancer gene influence tumor growth ...

In mantle cell lymphoma (MCL), an aggressive form of B-cell non-Hodgkin lymphoma, TP53 mutations are known to affect patients’ prognosis—but questions remain. What does the heterogeneity of TP53 ...

A new proof-of-concept method reliably engineered a hotspot mutation of SF3B1, a gene-splicing gene, into diverse cancer cell lines, outperforming other contemporary editing approaches. Oncogenesis ...

Autism spectrum disorder is complex; it present differently in different patients, and the causes are still unclear, even though hundreds of small ... | Genetics And Genomics ...

Genetic mutations aren't always a bad thing. A groundbreaking new study suggests that mutations on a single gene may actually be beneficial when it comes to Alzheimer’s disease. For the study, Dr.

Researchers in Class of 1942 Professor of Chemistry Matthew D. Shoulders' lab have uncovered a sinister hidden mechanism that ...

Believed to be caused by a mix of genetic and environmental factors, Parkinson’s disease is a chronic, progressive disease that affects the central nervous system, particularly the motor system, ...

Using cortical organoids from individuals with autism, researchers tracked gene activity over development. Early ...

A new study suggests a gene mutation could have a protective effect against Alzheimer's. The research looked specifically at blood stem cells, which live in the bone marrow and make different types of ...