Cigarette smoke accelerates eye aging by causing epigenetic changes that block the eye's natural repair genes.

CTCF is widely recognized for its essential role in mediating chromatin loops to regulate gene expression, particularly by modulating enhancer-promoter (EP) interactions. However, acute depletion of ...

Dr. Yasuhiro Arimura studies chromatin, the mixture of DNA and DNA-packaging proteins. Chromatin is “marked” with numerous chemical or structural cues that enable cells to organize DNA and manage how ...

Immune cells in the blood may be intimately involved with Alzheimer’s pathogenesis in the brain. At least, according to their chromatin. A study published January 31 in Neuron reported that in people ...

This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...

Experiencing multiple acute stresses at the same time, as in natural disasters or mass shootings, can leave lasting memory scars. New research from the University of California, Irvine suggests that ...

Phase separation in nuclear cell biology represents a conceptual framework for understanding how cells spatially and temporally regulate gene expression.