Scientists from Oxford's Radcliffe Department of Medicine have achieved the most detailed view yet of how DNA folds and functions inside living cells, revealing the physical structures that control ...

For the first time, researchers have succeeded in developing an artificial DNA base pair that is based on a different chemical force than natural genetic material. While the common natural DNA ...

Accurate RNA splicing is essential for gene expression and human health, yet predicting how DNA sequence variations affect ...

Metal-mediated base pairing is an emerging paradigm in which metal ions replace or complement natural hydrogen bonds between nucleobases in DNA and RNA duplexes. By coordinating transition metals such ...

Scientists have for the first time been able to build a organism containing a new, synthetic pair of DNA units, marking a breakthrough in the field of synthetic biology that has major implications for ...

Engineers at the University of Pennsylvania and Rice University have refined a technology for editing individual genetic "base pairs" to a new level of precision, opening the door to safer, more ...

Computational chemists at the University of Amsterdam's Van 't Hoff Institute for Molecular Sciences have developed a comprehensive software suite to create accurate models of DNA in biomolecular ...

This image illustrates the chemical structures of the five main nucleobases found in DNA and RNA. The pyrimidines, thymine (DNA), uracil (RNA), and cytosine are shown on top while the purines, adenine ...

Adenine was first discovered in 1885 by the German physiologist Albrecht Kossel. He isolated adenine from the pancreas of oxen and named it "adenine" derived from the Greek word "aden," meaning gland.