A duplicated gene evolved into a switch that determines sex in frogs, revealing how evolution can safely reshape critical ...

Sometimes, in genetics, two wrongs do make a right. A research team has recently shown that two harmful genetic variants, ...

AlphaGenome is a DNA sequence model that advances regulatory variant-effect prediction to understand genome function.

A University of California San Diego-led team has discovered that restoring a key cardiac protein called connexin‑43 in a ...

Gene-editing tools like CRISPR have unlocked new treatments for previously uncurable diseases. Now, researchers at the ...

In Lewis Carroll's "Through the Looking-Glass," Alice is stuck in a never-ending race with the Red Queen yet never gains a ...

When two defective gene variants combine, normal protein function can sometimes be restored.

Johns Hopkins researchers have developed a powerful new AI tool called Splam that can identify where splicing occurs in genes—an advance that could help scientists analyze genetic data with greater ...

Gene-set analysis seeks to identify the biological mechanisms underlying groups of genes with shared functions. Large language models (LLMs) have shown promise in generating functional descriptions ...

A new comprehensive analysis has revealed that major depressive disorder alters both the physical architecture and the ...

Randomized trials of platelet function and genetic testing to guide antiplatelet decisions following PCI have produced notoriously mixed results: now, an updated consensus document aims to fill some ...