Sickle cell trait is where a person carries a single mutated hemoglobin A beta subunit allele. Usually, two mutated copies of this gene are needed to cause sickle cell disease (SCD). Typically, people ...

Scientists found the cellular response to low oxygen also increases fetal hemoglobin expression in adults, which could lead to novel treatments for some common genetic anemias. Scientists at St. Jude ...

Gene therapy that alters hemoglobin genes may be an answer to curing sickle cell disease (SCD) and beta thalassemia. These two common life-threatening anemias afflict millions of individuals across ...

Beta thalassemia minor is a blood disorder that can cause mild anemia, but it often doesn't show symptoms. If both parents carry the trait for beta thalassemia minor, there's a higher risk of having a ...

(MEMPHIS, Tenn. – October 12, 2022) Scientists at St. Jude Children’s Research Hospital have shown how a protein responsible for adapting to low oxygen conditions (hypoxia), causes increased ...