For many people diagnosed with cancer, treatment with immune checkpoint inhibitors (ICIs) has dramatically extended lives.

For many people diagnosed with cancer, treatment with immune checkpoint inhibitors (ICIs) has dramatically extended lives. Some of these treatments, such as Keytruda and Opdivo, have become familiar ...

Leronlimab-mediated CCR5 blockade modulates T-Cell exhaustion pathways and PD-L1 Biology relevant to ICI responseDurable Clinical Observations ...

When immune checkpoint inhibitors are used in cancer treatment, in some cases it can lead to severe inflammation and damage to heart tissue. Histology images of mouse heart tissue illustrate the ...

In a study published in February 2026 in JCO Oncology Practice, investigators from Sweden report that influenza vaccination during treatment with immune checkpoint inhibitors was associated with ...

Immune checkpoint inhibitors (ICIs) were associated with modest protective effects for patients with asthma, according to new research being presented at the 2026 AAAAI Annual Meeting.

Scientists have identified a hidden barrier that prevents immunotherapy from working against a rare liver cancer. Immunotherapy, which activates the body’s own immune system to kill cancer cells, has ...

AltruBio Inc. (“AltruBio” or “the Company”), a clinical stage biotech company developing novel immune checkpoint enhancers to address the unmet need in immunological and inflammatory diseases, with a ...

Immunotherapy—which activates the body's own immune system to kill cancer cells—has not worked well against a rare and fatal ...

A novel immune checkpoint vaccine induced antigen-specific food allergy tolerance in mice, preventing anaphylaxis. Learn more.

Immune system activation and activity is regulated through stimulatory or inhibitory ligand-receptor interactions collectively termed immune checkpoints. 1 Stimulatory interactions give the immune ...