The Alzheimer’s enigma has puzzled researchers for decades. More than 7 million Americans are living with the neurodegenerative condition, and it’s projected that by 2060, that number will double.

Lithium, a naturally occurring trace element in the brain, may be able to unlock a key medical mystery: why some people develop Alzheimer’s disease and others don’t, despite similar brain changes. In ...

* Reduced lithium levels were found in brain regions essential for memory and decision-making * Amyloid plaques trap lithium, worsening disease progression from mild //cognitive impairment to ...

Endogenous lithium may have a physiological role that affects brain aging and vulnerability to Alzheimer's disease, postmortem human samples and mouse experiments suggested. Of 27 abundant and trace ...

Lithium was the only metal that had markedly different levels across groups and changed at the earliest stages of memory loss. Its levels were high in the cognitively healthy donors but greatly ...

In a mouse model of Alzheimer’s disease, lithium deficiency (right) dramatically increased amyloid beta deposits in the brain compared with mice that had normal physiological levels of lithium (left).

Can lithium’s effect on daily activity patterns reveal who will benefit from treatment? A six-week trial finds circadian shifts emerge early, before mood improves, hinting at a biological clue to ...

A first-ever study from the U.S. Geological Survey found roughly 40 percent of groundwater contains lithium above EPA’s health reference level. The U.S. Geological Survey mapped for the first time ...