In recent years, cancer researchers have made major breakthroughs by using the body's immune system to fight cancer. One of ...

An Indian review reveals how macrophages are reprogrammed inside breast tumours, helping cancer grow and spread while opening new treatment pathways.

Researchers say study results provide a clear rationale for developing therapies that target LCN2 in lung cancer patients.

Several subsets of macrophage have been found to closely associate with metastasis-initiating cells in the tumor microenvironment. A team of researchers at the Johns Hopkins Kimmel Cancer Center (MD, ...

Immune checkpoint inhibitors (ICIs) are a form of immunotherapy that activates anti-tumor immune cells. In the context of ...

Tumors are notoriously difficult to study in their natural habitat - body tissues - but a new synthetic tissue environment may give cancer researchers the next-best look at tumor growth and behavior.

Breast cancer cells, when disseminated to other secondary organs such as the lungs, may stay in a dormant state for years, even decades. But the mechanisms that limit their expansion are not well ...

A protein made by stressed cancer cells helps lung and pancreatic tumors evade the immune system, a new study shows. Led by ...

After months of shrinking scans, the tumors suddenly came roaring back. Oncologists have seen this pattern for years in patients on immunotherapy and targeted drugs: a dramatic initial response, then ...

Cancer cells such as these are being targeted -- and hopefully eradicated -- by researchers studying the impact of 'inflammaging," which looks at the relationship between cancer, inflammation and ...