There is a high unmet need for accessible, affordable, and high-quality fertility care, as approximately 1 in 6 people are affected by infertility worldwide. While meiotic failure is a major cause of ...

All cells in the body arise from a single fertilized egg. From this single origin, various specialized cells with widely differing tasks evolve through a process called cellular differentiation.

For stem cells to differentiate into the appropriate cell-type, transcription factors (TFs) must be tailored to highly specific expression patterns of lineage-specific genes. Abnormalities in the ...

Spurred by the discoveries of human pluripotent stem cell culture by James Thomson in the 1990s and the induction of pluripotency from adult cells by Shinya Yamanaka in the 2000s, therapeutics derived ...

Northeastern University scientists have discovered that a protein in the human brain could potentially be used to grow new neurons in the lab and enhance brain processes affected by aging or ...