Gut

Serum creatinine as both yardstick and predictor: reading chronic kidney disease in the global CLEARED cohort

We read the global analysis of chronic kidney disease (CKD) in cirrhosis by Wong et al with great interest.1 Assembling 7040 ...
Gut

Decoding intestinal metaplasia: a step towards understanding gastric tumourigenesis

Tissue epithelia maintain their lineage identity under normal conditions but occasionally undergo ‘reprogramming’ into ...
gut.bmj

Efficacy of gut-brain neuromodulators and brain-gut behaviour therapies for irritable bowel syndrome: systematic review and network meta-analysis

Background Irritable bowel syndrome (IBS) is a disorder of gut-brain interaction, with some recommended treatments targeting brain-gut axis dysfunction. Objective To compare relative efficacy of ...
gut.bmj

Early high-energy enteral nutrition in acute pancreatitis: overfeeding and respiratory risk in high-risk patients

I read the GOULASH trial with great interest. This multicentre, double-blind randomised clinical trial compared early high-energy enteral nutrition (30 kcal/kg/day) with a gradually increasing energy ...
gut.bmj

Development of an index to define overall disease severity in IBD

Background and aim Disease activity for Crohn's disease (CD) and UC is typically defined based on symptoms at a moment in time, and ignores the long-term burden of disease. The aims of this study were ...
gut.bmj

Acute upper gastrointestinal bleeding in the UK: patient characteristics, diagnoses and outcomes in the 2007 UK audit

Objective To describe the patient characteristics, diagnoses and clinical outcomes of patients presenting with acute upper gastrointestinal bleeding (AUGIB) in the 2007 UK Audit. Design Multi-centre ...
gut.bmj

Fucosyltransferase 2 (FUT2) non-secretor status and blood group B are associated with elevated serum lipase activity in asymptomatic subjects, and an increased risk for chronic ...

3 The Charles Bronfman Institute for Personalized Medicine, Genetics of Obesity & Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, USA 4 Institute for Community ...
gut.bmj

Prevalence and outcomes of acute pancreatitis in COVID-19: a meta-analysis

The study by Pandanaboyana et al 1 showed that acute pancreatitis (AP) patients with COVID-19 had a significantly higher mortality than those without COVID-19. Nevertheless, a similar trend of ...
gut.bmj

High-protein diets alleviate tumour growth and drug resistance by promoting AKT aggregation and turnover

Background Despite the long-standing recommendations of high-protein diets for patients with cancer, the precise mechanisms of this dietary approach in benefiting tumour suppression and enhancing ...
gut.bmj

Influence of timing of maternal antibiotic administration during caesarean section on infant microbial colonisation: a randomised controlled trial

Objective Revised guidelines for caesarean section (CS) advise maternal antibiotic administration prior to skin incision instead of after umbilical cord clamping, unintentionally exposing the infant ...
gut.bmj

Guidelines for the management of inflammatory bowel disease in adults

7 Department of Paediatrics, St George's Hospital, London, UK 8 Department of Gastroenterology, St. Mary's Hospital, London, UK 9 Department Gastroenterology, University Hospital of North Tees, UK The ...
gut.bmj

Diagnostic accuracy study of anorectal manometry for diagnosis of dyssynergic defecation

1 National Centre for Bowel Research and Surgical Innovation and GI Physiology Unit, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK Objective The ...