Regarding the pediatric population, mold-active antifungal prophylaxis is recommended for pediatric patients at high risk of IFD, including a subgroup of children with ALL. Regarding the pediatric ...

The CAPTIVATE trial met its target of at least 20 responders among the first 40 participants before all 40 completed part A. Dianthus Therapeutics announced an early “go” decision for claseprubart for ...

Gastrointestinal involvement in systemic mastocytosis (SM) is a common complication and often leads to endoscopic findings. Gastrointestinal (GI) symptoms are the second most frequent clinical ...

Chronic inflammatory demyelinating polyneuropathy (CIDP) is a rare acquired autoimmune neurological disorder in which both T-cell-mediated and humoral immune mechanisms target healthy myelinated ...

Survival outcomes were similar with hypomethylating agents (HMAs) alone and an HMA plus venetoclax despite higher overall response rates. Investigators retrospectively evaluated 140 patients with TP53 ...

According to the physicians who responded to the survey, patients experienced a mean of 3.8 ± 9.8 months between the initial onset of EGPA signs/symptoms and their first consultation with a healthcare ...

The use of semaglutide has been associated with improvement of treatment-resistant mast cell activation symptoms in an overweight patient with SM. Glucagon-like peptide-1 receptor agonists (GLP-1RAs) ...

The antibodies were slightly more common in double seronegative MG, at 3.9%, than in seropositive MG, at 1%. In patients with suspected myasthenia gravis (MG), LRP4-IgG antibodies are rare, with poor ...

Individuals with advanced liver disease may also experience significant weight loss due to nausea and poor appetite. Candidates for liver transplantation may need to gain weight to optimize surgical ...

Intravenously administered zaltenibart was shown to be safe and effective in phase 2 clinical trials. Enrollment is under way to recruit patients for a phase 3 study designed to assess intravascular ...

Although 94% of HCPs agreed that transparent communication improves their understanding of patient preferences, only 57% of patient advocacy group representatives concurred. Physicians and patient ...

Literature on pediatric IgG4-RD is relatively scarce, meaning that much about the disease course in this patient population is unknown. Immunoglobulin G4-related disease (IgG4-RD) is a rare ...