Unique instruments automate sample preparation, quality control for cryo-electron microscopy

Cryo-electron microscopy (cryo-EM) can help scientists determine the three-dimensional structure of proteins in unprecedented detail. Jacques Dubochet, former group leader at EMBL, shared the 2017 ...
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Drawing microscopic patterns with electrons

Today we're looking at Electron Beam Lithography using a scanning electron microscope.

Ultrafast scanning tunneling microscopy reaches the quantum mechanical space-time limit for the first time

Werner Heisenberg's famous uncertainty principle describes one of the most intriguing features of quantum physics: certain pairs of physical quantities describing a particle, such as position and ...
Nature

Making samples one billion times bigger lets simple microscopes pinpoint amino acids

Stretching protein samples in all directions pulls molecules farther apart, allowing them to be visualized using only light ...
Hackaday

Converting A Scanning Electron Microscope Into A TEM Is Surprisingly Easy

Although both a SEM and a TEM are electron microscopes, their working principles and images are very different. Whereas an SEM uses secondary electrons ejected after bombarding a sample’s surface with ...

Cryo-EM imaging reveals how a molecular gate lets bulky proteins pass cell membranes intact

How large, fully folded proteins can pass through cell membranes without destroying them has long been one of the open ...